The following list contains all villains that were seen or mentioned in Mighty Med. There is at total of 40 villains and they all work for the League of Villains and the bowling League of Heroes.
Seen[]
- The Annihilator, first mentioned in Saving the People Who Save People, and first appeared in There's a Storm Coming
- The Black Falcon, first mentioned in I, Normo, and first appeared in Atomic Blast From the Past
- Bob (Dreadlock's henchman), first appeared in Two Writers Make a Wrong
- Crimson Demon, first appeared in It's Not the End of the World
- Disembowler, first appeared in Lockdown
- Dr. Wrath, first appeared in Mighty Mad (Parody of Lord Voldermort from Harry potter
- Dreadlock, first appeared in Two Writers Make a Wrong
- Experion, former superhero. First appeared in The Friend of My Friend Is My Enemy
- The Exterminator, first appeared in Lockdown
- Machete Man
- Megahertz, first appeared in Saving the People Who Save People
- Micros, first appeared in Sm’oliver’s Travels
- Mort, first appeared in Living the Dream
- Mr. Terror, first appeared in Living the Dream
- Nightstrike
- Red Scare, first appeared in Atomic Blast from the Past
- Revengeance, first appeared in Lockdown
- Sewer Rat, first appeared in Lockdown
- Skylar Storm (while evil only; temporarily), first appeared in How the Mighty Med Have Fallen
- Slaughter Master, first mentioned in Future Tense, and first appeared in The Key to Being a Hero
- Sonic Shriek, first appeared in Fantasy League of Superheroes
- Soul Slayer, first appeared in Guitar Superhero
- The Incapacitator, first appeared in Lab Rats vs. Mighty Med
- The Incinerator, appeared in The Mother of All Villains
- Wallace and Clyde, first appeared in Saving the People Who Save People
- Wi-Fi, first appeared in Free Wi-Fi
- Mr Terror: First appeared in The Mother of All Villains
- Chaz: First appeared in New Kids Are the Docs
- Gulliver: First appeared in New Kids Are the Docs
Mentioned[]
- Argento, mentioned in The Mother of All Villains as the former boss of Bridget. He is deceased.
- Blood Chief, mentioned in How the Mighty Med Have Fallen.
- Counterfeit, mentioned by Wi-Fi in Free Wi-Fi.
- Flesh Mangler, mentioned by Megahertz in The Dirt on Kaz & Skylar
- The Impaler, mentioned in Saving the People Who Save People.
- The Harpooner, mentioned in Less Than Hero.
- Murderface, mentioned by Megahertz in The Dirt on Kaz & Skylar.
- Professor Slime, was mentioned in the episode Atomic Blast From the Past.
- Razor Claw, first mentioned in Free Wi-Fi.
- Skull Face, mentioned in Future Tense.
- Vanquisher, mentioned in Alan's Reign of Terror.